Gallbladder attacks can cause intense, sudden pain in the upper abdomen, often sending patients to the emergency room. These episodes occur when gallstones temporarily block the bile ducts, interrupting the normal flow of bile from the gallbladder to the intestine. While gallstone disease often develops silently, an attack may be the first clear sign that something is wrong. Medical care remains essential for proper diagnosis and long-term treatment, but knowing how to manage symptoms in the moment can help reduce discomfort until evaluation is possible.

What to Know About the Gallbladder

The gallbladder is a small, pear-shaped organ situated beneath the liver on the right side of the abdomen. Despite its modest size, the gallbladder plays an important role in the digestive process as a storage reservoir for bile. Bile, a digestive fluid produced by the liver, is primarily made up of water, bile salts, cholesterol, and bilirubin. After being produced by the liver, bile travels through small tubes called bile ducts. Some of this bile flows directly to the small intestine, but much of it is diverted to the gallbladder for storage between meals.

When you eat, especially foods containing fat, your body releases hormones that signal the gallbladder to contract. This contraction pushes the stored bile through the common bile duct and into the small intestine where it helps break down fats into smaller particles that can be more easily absorbed by the body. In a healthy digestive system, this process happens smoothly with each meal. Sometimes, however, the chemical balance of bile can change, causing solid particles to form within the gallbladder. These particles can disrupt normal bile flow and lead to complications.

What Are Gallstones?

Gallstones (cholelithiasis) form when substances in bile crystallize into solid deposits within the gallbladder. These stones can range in size from tiny grains of sand to golf ball-sized masses, though most remain small enough to pass through the bile ducts. Some people develop just one gallstone, while others may have hundreds. Approximately 10-15% of adults have gallstones, though many never experience symptoms. Several factors can increase the risk of developing gallstones:

  • High cholesterol levels: When bile contains more cholesterol than can be dissolved by bile salts, the excess can form crystals that eventually become stones.
  • Incomplete gallbladder emptying: If the gallbladder doesn’t contract regularly or completely, bile becomes increasingly concentrated, creating conditions that favor stone formation.
  • Obesity: Excess weight increases cholesterol production and often reduces gallbladder emptying efficiency, substantially raising gallstone risk.
  • Rapid weight loss: Losing weight quickly can cause the liver to secrete extra cholesterol into bile, increasing stone risk.
  • Age and gender: Women are twice as likely as men to develop gallstones, particularly during pregnancy or while taking hormone therapy. Risk also increases after age 40.
  • Family history: Genetic factors significantly influence gallstone formation, with risk increasing if close relatives have had gallstones.
  • Certain medical conditions: Diabetes, liver disease, and some blood disorders can increase gallstone risk through various mechanisms.1

    What Is a Gallbladder Attack?

    A gallbladder attack, medically known as biliary colic, occurs when a gallstone temporarily blocks a bile duct and prevents normal bile flow. This blockage causes pressure to build within the gallbladder as it continues to contract against the obstruction. As pressure increases, inflammation may develop, intensifying symptoms and potentially leading to complications if left untreated. Unlike many digestive disorders that cause vague discomfort, gallbladder attacks typically produce distinctive symptoms that help differentiate them from other conditions.

    Gallbladder attacks usually develop after eating a meal and are even more likely when the meal is high in fat. The pain intensifies rapidly, often reaching peak severity within an hour, and can last from 30 minutes to several hours. The discomfort tends to be steady and severe, making it difficult to find a comfortable position. Most attacks resolve on their own when the stone either passes through the duct or falls back into the gallbladder.

    One of the telltale signs of a gallbladder attack is sharp, intense pain that begins in the upper right abdomen and often radiates to the right shoulder or between the shoulder blades. This pain typically doesn’t improve with position changes or passing gas, distinguishing it from other types of digestive discomfort. Nausea and vomiting frequently accompany these attacks, along with bloating and general digestive distress. If the attack progresses to a more serious condition such as acute cholecystitis or common bile duct blockage, additional symptoms may appear, like fever, jaundice, or persistent vomiting.2

    How to Manage a Gallbladder Attack

    When a gallbladder attack strikes, the intense pain can be overwhelming and frightening. While definitive treatment typically requires medical intervention, there are several evidence-based strategies that may provide temporary relief while you arrange for proper medical care or determine if emergency treatment is necessary. These measures won’t resolve the underlying gallstone issue, but they can help make the pain more manageable during those critical first hours:

    • Stop eating immediately: Consuming food causes the gallbladder to contract, potentially worsening pain if a stone is obstructing a bile duct. Fast completely until the pain subsides.
    • Apply heat to the painful area: A heating pad or warm compress placed on the upper right abdomen can help relax the muscles and reduce pain intensity. Use for 10-15 minutes at a time with a thin cloth between the heat source and skin to prevent burns.
    • Find a position that minimizes pain: Many people experience relief by sitting upright and leaning slightly forward or by lying on their left side with knees drawn toward the chest. Experiment carefully to find what works best.
    • Consider over-the-counter pain medication: Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen may help reduce inflammation and manage pain. Follow package directions and avoid these medications if you have certain medical conditions or are taking other medications that might interact.
    • Stay hydrated with clear fluids: Sip water or clear broth to prevent dehydration, especially if vomiting occurs. Avoid alcohol, caffeine, and acidic juices, which may worsen symptoms.
    • Practice controlled breathing techniques: Slow, deep breaths can help manage pain intensity and reduce the anxiety that often accompanies severe discomfort. Inhale deeply through your nose, hold briefly, then exhale slowly through your mouth.

    While these measures may provide temporary relief, certain symptoms indicate a potential emergency requiring immediate medical attention. Seek emergency care if your pain lasts more than five hours, if you develop fever or chills, if you notice yellowing of the skin or eyes, if your stools become light-colored or your urine darkens, or if you experience persistent vomiting. These signs may indicate serious complications such as infection, complete bile duct blockage, or inflammation affecting the pancreas.

    Contact a Gastroenterologist

    Gallbladder attacks can cause severe pain and disrupt your daily life. If you’ve experienced symptoms that suggest a gallbladder attack, don’t wait for another episode to seek help. The gastroenterologists at Cary Gastro specialize in diagnosing gallbladder conditions and can help you understand your treatment options, from lifestyle modifications to surgical interventions when necessary. Contact us today to schedule an appointment and take the first step toward managing gallbladder pain effectively.


    1https://www.niddk.nih.gov/health-information/digestive-diseases/gallstones/symptoms-causes
    2https://www.hopkinsmedicine.org/health/conditions-and-diseases/what-causes-a-gallbladder-attack